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Texas Department of Insurance
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2024 Prescription drug cost transparency review: Health benefit plan issuers

In 2024, 34 health benefit plan (HBPs) issuers reported the 25 most frequently prescribed drugs and some aspects of their prescription drug spending. TDI collected the data under Texas Insurance Code 1369.502 and 1369.503. TDI reports only what the HBPs supplied and doesn’t audit it.

25 Most frequently prescribed drugs

The table below shows how many issuers reported each drug. Of 98 drugs reported, at least 16 responding issuers prescribed these 25 drugs.

We removed duplicates and combined data for drugs that were reported separately by brand and generic names, different dosages, and standard and extended-release versions.

Drug name Drug class Conditions treated Total issuers Percent of total issuers
Losartan [1] angiotensin receptor antagonists high blood pressure 32 94%
Atorvastatin statins high cholesterol 32 94%
Levothyroxine thyroid drugs hypothyroidism 31 91%
Lisinopril ACE inhibitors high blood pressure 31 91%
Amlodipine calcium channel blockers high blood pressure; angina 30 88%
Prednisone corticosteroids inflammation 30 88%
Rosuvastatin [2] statins high cholesterol 29 85%
Metformin [3] antidiabetic agents type 2 diabetes 28 82%
Amoxicillin [4] antibiotics bacterial infection 28 82%
Gabapentin anticonvulsants seizures; shingles pain; restless leg syndrome 28 82%
Albuterol bronchodilators bronchospasm; asthma 28 82%
Azithromycin antibiotics bacterial infection 27 79%
Amoxicillin And Clavulanate Potassium antibiotics; beta-lactamase inhibitors bacterial infection 26 76%
Escitalopram SSRIs depression 25 74%
Amphetamine And Dextroamphetamine [5] stimulants ADHD; narcolepsy 24 71%
Montelukast leukotriene modifiers asthma 24 71%
Sertraline SSRIs depression; panic; anxiety; or obsessive-compulsive symptoms 23 68%
Pantoprazole proton pump inhibitors gastroesophageal reflux disease 23 68%
Metoprolol beta blockers high blood pressure 21 62%
Trazodone SARIs depression 20 59%
Semaglutide incretin mimetics type 2 diabetes 18 53%
Bupropion antidepressants depression 18 53%
Ibuprofen NSAIDs mild to moderate pain; fever; and inflammation 18 53%
Hydrochlorothiazide diuretic high blood pressure; fluid retention 16 47%
Omeprazole proton pump inhibitors gastroesophageal reflux disease 16 47%

[1] Losartan appeared twice in two submissions
[2] Rosuvastatin appeared twice in a single submission
[3] Metformin appeared twice in five submissions and three times in another
[4] Amoxicillin appeared twice in a single submission
[5] Amphetamine And Dextroamphetamine appeared twice in a single submission

Premium reductions due to utilization management

The issuers reported savings of $375 million due to specialty drug utilization management, $110 million more than the previous year.

Drug spending data

These tables show HBPs responses on prescription drug spending. In each case, “Number reporting this amount” is how many respondents reported changes in the ranges indicated.

Net spending change on prescription drugs Number reporting this amount
-100.0% 1
-85.0% 1
-77.0% 1
-62.2% 1
-30.5% 1
-25.0% 1
-20.0% 1
-19.0% 1
-11.5% 1
-9.0% 1
-7.6% 1
-6.1% 1
-5.3% 1
1.9% 1
2.4% 1
3.5% 1
6.0% 1
7.0% 1
9.8% 1
10.1% 1
12.0% 1
12.4% 1
13.6% 1
14.0% 2
19.2% 1
19.8% 1
22.3% 1
23.6% 1
25.7% 1
30.0% 1
51.0% 1
61.0% 1
62.5% 1
67.0% 1
Premium change due to prescription drugs Number reporting this amount
-13.0% 1
-4.6% 1
-0.5% 1
-0.2% 2
0.0% 4
0.1% 1
1.8% 1
2.0% 2
2.4% 2
2.6% 3
2.7% 1
3.0% 1
4.0% 1
6.0% 1
10.8% 1
13.6% 1
14.6% 1
19.3% 1
22.0% 1
26.0% 1
31.6% 1
39.3% 1
42.0% 1
43.0% 1
48.7% 1
80.8% 1
144.0% 1
Specialty drugs under use management Number reporting this amount
0.0% 3
2.9% 1
14.0% 1
23.4% 2
38.5% 1
48.0% 1
50.6% 1
56.5% 1
56.6% 1
60.8% 4
65.0% 1
68.0% 1
69.0% 1
71.0% 1
79.0% 1
83.0% 1
85.0% 2
86.7% 1
87.0% 1
88.0% 1
89.0% 4
96.0% 1
100.0% 3

For more information, contact: LifeHealth@tdi.texas.gov

Last updated: 5/28/2025